Genvoya (Elvitegravir / Cobicistat / Emtricitabine / Tenofovir)

Genvoya (Elvitegravir / Cobicistat / Emtricitabine / Tenofovir) Medication Information:

What is Genvoya?

Genvoya is a prescription medicine indicated in the treatment of HIV-1 infection. It contains 4 active medicaments namely:

• Elvitegravir - an integrase strand transfer inhibitor (INSTI) that helps block HIV from integrating into the human DNA, preventing the virus from multiplying.
• Cobicistat - a pharmacokinetic enhancer that boosts the effectiveness of Elvitegravir by inhibiting liver enzymes that would otherwise break it down.
• It is used to treat Paget's disease, a disorder in which aberrant bone remodeling results in weak and malformed bones.
• Emtricitabine - a nucleoside reverse transcriptase inhibitor (NRTI) that helps block the reverse transcriptase enzyme, which HIV needs to multiply.
• Tenofovir Alafenamide - another NRTI that also inhibits the reverse transcriptase enzyme, reducing HIV's ability to replicate.

Genvoya is used as part of antiretroviral therapy (ART) in adults and children aged 12 and older who weigh at least 25 kg and who have never received HIV treatment before or are switching from another regimen with stable viral suppression, for those considering this medication to research the Genvoya price, as costs may vary depending on your location and insurance coverage.

Uses and Benefits of Genvoya:

Some of the common uses of Genvoya include:

• Treatment of HIV-1 Infection: Genvoya is prescribed to treat HIV-1 in adults and children aged 12 and older (who weigh at least 25 kg). It is used in patients who are treatment-naive (those who have not previously received HIV medications) and are switching from a stable antiretroviral regimen with no history of treatment failure or resistance to the components of Genvoya.
• Part of Antiretroviral Therapy (ART): It is used as part of ART, which involves combining medications to suppress the viral load, prevent the progression of HIV to AIDS, and improve immune function.

Side Effects of Genvoya:

Common side effects associated with Genvoya may include:

• Nausea
• Fatigue
• Dizziness
• Abdominal pain
• Diarrhea
• Headache
• Rash
• Sleep disturbances
• High cholesterol levels
• Weight gain
• Depression
• Kidney problems

How to use Genvoya?

• Take one tablet once daily, exactly as your healthcare provider prescribes.
• Genvoya should be taken with food to enhance its absorption.
• Do not crush, chew, or split the tablet; swallow it whole with water.
• Take Genvoya at the same time every day to maintain steady levels of the medication in your body.

Genvoya Drug Interactions:

Here are some key drug interactions:

• Rifampin and Rifabutin.
• St. John's Wort
• Anticonvulsants (e.g., Carbamazepine, Phenobarbital, Phenytoin).
• Antacids and Proton Pump Inhibitors (e.g., Omeprazole, Lansoprazole).
• Certain Antifungals (e.g., Ketoconazole, Itraconazole).
• Certain Antiviral Medications (e.g., Boceprevir, Telaprevir).
• Certain Blood Thinners (e.g., Warfarin, Rivaroxaban).
• Certain Antibiotics (e.g., Clarithromycin, Rifapentine).
• Certain Heart Medications (e.g., Amiodarone, Diltiazem).

Genvoya Precautions:

Precautions to follow while taking Genvoya are:

• Genvoya may cause kidney problems, so regular monitoring of kidney function is essential. It is not advised for people with severe renal impairment.
• Genvoya may cause reduced bone mineral density. Individuals with a history of bone problems or osteoporosis should be cautious, and calcium or vitamin D supplements may be advised.
• People with pre-existing liver conditions, such as hepatitis B or C, should use Genvoya with caution. Monitoring liver function is suggested during treatment with this medication.
• Genvoya is not used for pre-exposure prophylaxis (PrEP) to prevent HIV infection. It should only be taken by those diagnosed with HIV-1.

Buy Genvoya Online:

If you are considering to buy Genvoya online, it's important to do so from a reputable and licensed pharmacy. LifeRx Pharmacy is one such online pharmacy that offers prescription medications, including Genvoya. You can visit our website to check the availability of Genvoya and other drugs, and they typically provide home delivery options for convenience. LifeRx Pharmacy offers competitive Genvoya prices, making it easier to manage treatment costs.

Can Genvoya be crushed?

No, Genvoya should not be crushed, split, or chewed. The tablet must be swallowed whole to ensure proper absorption and effectiveness of the medication. Crushing the tablet could alter how the drug is released and absorbed in your body, potentially reducing its efficacy. If you have trouble swallowing the tablet, consult your healthcare provider for alternative solutions.

Can Genvoya be used for pep?

No, Genvoya is not recommended for post-exposure prophylaxis (PEP). PEP is a short-term treatment used to prevent HIV infection after potential exposure and specific medications like Truvada or Descovy combined with other antiretroviral drugs are typically prescribed for PEP. Genvoya is primarily used for treating individuals already diagnosed with HIV-1.

Does Genvoya cause erectile dysfunction?

Erectile dysfunction does not occur with Genvoya. While it may cause various side effects, including nausea or fatigue, erectile dysfunction is not a well-documented issue with Genvoya. If you experience erectile dysfunction or any other concerning symptoms, it's important to discuss them with your healthcare provider for appropriate evaluation and management.

Does Genvoya cause hair loss?

Hair loss is not a commonly reported side effect of Genvoya. While Genvoya can have various side effects, hair loss is not typically listed among them. If you experience hair loss or other unexpected symptoms while taking Genvoya, consult your healthcare provider to determine the cause and discuss potential solutions.

Does Genvoya cause weight gain?

Genvoya may be associated with weight gain in some individuals, although it is not the most common side effect. Weight changes can vary from person to person. If you notice significant or unexpected weight gain, it is important to discuss it with your healthcare provider to assess its cause and manage any potential impact on your health. You can visit LifeRx Pharmacy's website to check the Genvoya cost and other medications.

References:

• https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/207561s002lbl.pdf
• https://www.genvoya.com/