Otezla (Apremilast)

Otezla (Apremilast) Medication Information:

What is Otezla Cream?

Otezla Cream is a new topical treatment for Psoriasis. Unlike traditional creams and ointments, Otezla incorporates innovative active ingredients that target the underlying causes of psoriasis, offering a more comprehensive approach to managing the condition. Its formulation is based on extensive research and clinical trials, making it a reliable option for those seeking relief from psoriasis symptoms, making Otezla cost boom all the time.

Uses and Benefits of Otezla Cream:

Uses:

• Plaque Psoriasis: Otezla is prescribed for adults with moderate to severe plaque psoriasis, particularly when other systemic therapies or phototherapy are deemed inappropriate. It helps reduce the severity and extent of psoriatic plaques, leading to clearer skin and improved physical appearance.
• Psoriatic Arthritis: Otezla effectively treats active psoriatic arthritis, which affects the joints in people with psoriasis. It alleviates joint pain, swelling, and stiffness, improving joint function and mobility.

Benefits of Otezla:

• Oral Administration: One of the primary benefits of Otezla is its oral form. Unlike biologic therapies that require injections or infusions, Otezla is taken as a pill, making it convenient and easy to use.
• Effective Symptom Relief: Clinical studies have shown that Otezla significantly reduces the severity of psoriasis plaques and relieves symptoms of psoriatic arthritis, substantially improving patients’ quality of life.
• Targeted Action: By specifically inhibiting PDE4, Otezla targets the underlying inflammatory processes without broadly suppressing the immune system. This targeted action helps minimize the risk of infections and other side effects commonly associated with systemic immunosuppressants.
• Improved Physical and Mental Well-being: Beyond physical symptom relief, Otezla has been associated with improvements in patient's mental health, including reductions in symptoms of depression and anxiety often linked to chronic inflammatory conditions.
• Long-term Safety: Otezla has a favorable safety profile with no requirement for regular blood monitoring, unlike many other systemic therapies for psoriasis and psoriatic arthritis.

Side Effects of Invokana:

Here are some of the most commonly reported side effects:

• Diarrhea
• Nausea
• Headache
• Upper Respiratory Tract Infections
• Weight Loss

While less common, these side effects have been reported by some Otezla users:

• Vomiting
• Abdominal Pain
• Fatigue
• Insomnia

Though rare, there are serious side effects associated with Otezla:

• Severe Allergic Reactions including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and trouble breathing.
• Severe Diarrhea, Nausea, or Vomiting.
• Mood Changes and Depression.

How to use Otezla?

• Otezla tablets should be swallowed whole with water. Do not crush, chew, or split the tablets. The Otezla price is higher, so wasting medicine is not wise.
• Otezla can be taken with or without food. If you experience nausea, taking it with food may help reduce this side effect.
• Try to take Otezla at the same time each day to maintain a consistent level of the medication in your bloodstream.

Otezla Drug Interactions:

• CYP450 Enzyme Inducers include Rifampin, Phenobarbital, Carbamazepine, and Phenytoin. These drugs are strong inducers of the CYP450 enzyme system, particularly CYP3A4, which can decrease the plasma concentration of Otezla, potentially reducing its effectiveness.
• CYP450 Enzyme Inhibitors include Ketoconazole, Itraconazole, Clarithromycin, Erythromycin. These drugs are strong inhibitors of CYP3A4, which can increase the plasma concentration of Otezla, potentially increasing the risk of side effects.
• Other immunosuppressants include Methotrexate and Cyclosporine. The concurrent use of Otezla with other immunosuppressants has not been extensively studied, and there may be an increased risk of immunosuppression and infection.
• Antacids and Acid Suppressants including Omeprazole and Ranitidine. There is no significant interaction reported between Otezla and antacids or acid suppressants.

Buy Otezla Online:

Otezla is a prescription medication for certain types of psoriasis and psoriatic arthritis. For those considering to buy Otezla online, it's crucial to ensure you use a reputable and licensed pharmacy. Otezla cost is usually high when buying from an offline pharmacy. Check e-pharmacies like LRP for better Otezla prices.

Consulting with your doctor before making an online purchase is also advisable to ensure that Otezla is the right treatment for your condition and that you understand the proper dosage and potential side effects. At LifeRxPharmacy you can get the best Otezlar prices with a valid prescription.

Do Otezla side effects go away?

There is a chance that every medication will have adverse effects, and Otezla is no exception. When you continue taking the medication, these adverse effects normally disappear after a few weeks of treatment.

Does Otezla cause hair loss?

No. Otezla does not cause hair loss. On the other hand, scratching could cause temporary hair loss if you have plaque psoriasis on your scalp.

Is Otezla a DMARD?

Yes, Otezla is a DMARD. The class of drugs called Disease-Modifying Antirheumatic Drugs (DMARDs) is mostly used to treat rheumatoid arthritis. Psoriasis and psoriatic arthritis are conditions that are treated with Otezla.

Does Otezla help with fatigue?

Otezla works by inhibiting the enzyme phosphodiesterase 4 (PDE4), which plays a role in the inflammatory processes associated with psoriasis and psoriatic arthritis. By reducing inflammation, Otezla helps to alleviate the symptoms of fatigue conditions.

Can Otezla cause joint pain?

No, Otezla does not cause joint pain. Its main function is to reduce inflammation and manage symptoms such as joint pain, but the exceptions can be there.

References:

• https://www.otezla.com/
• https://www.psoriasis.org/otezla/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517531/