Revolade (Eltrombopag)

Revolade (Eltrombopag) Medication Information:

What is Revolade?

Revolade (Eltrombopag) is a brand-prescribed medication for treating thrombocytopenia with low platelet counts. It is an agonist of the thrombopoietin receptor that increases bone marrow platelet synthesis.

Patients who have not reacted well to previous therapies should try it. Additionally, it is employed to raise platelet counts before starting interferon-based treatment. Additionally, individuals who have not responded to immunosuppressive medication might get it as an additional treatment.

Uses and Benefits of Revolade:

Some of the commonly listed uses and benefits of Revolade include:

• When all other therapies have failed, adults and children older than one-year-old with persistent immunological thrombocytopenia (ITP) can be treated with Revolade.
• By increasing platelet counts, it lessens the frequency of bleeding episodes. It can improve overall quality of life by reducing symptoms like tiredness and bruises by raising platelet levels.
• Patients with low platelet counts who have chronic hepatitis C and are about to begin interferon-based therapy are prescribed Revolade.
• When immunosuppressive medication has not produced the desired results in individuals with severe aplastic anemia (SAA), Revolade is used as an additional treatment.
• It increases platelet levels and may help people with SAA have higher blood cell counts overall.
• It might decrease the need for frequent blood transfusions.

Side Effects of Revolade:

Some Common Side Effects of Revolade include:

• Headache
• Nausea
• Exhaustion
• Diarrhea
• Increased Hepatic Enzymes

Some serious side effects that need medical interventions include:

• Liver failure and other severe liver issues are possible. Jaundice, or yellowing of the skin or eyes.
• Serious blood clotting events such as myocardial infarction (heart attack), pulmonary embolism (PE), stroke, and deep vein thrombosis (DVT).
• Severe allergic reactions, rash, itching, swelling, or breathing difficulties.
• On rare occasions, myelodysplastic syndromes (MDS) or other hematologic malignancies may occur with Revolade.

How to use Revolade?

• Revolade comes as a tablet for oral use. It is administered orally, or through the mouth.
• Adults and children (≥1 year) with chronic immune thrombocytopenia (ITP) should begin with 50mg once a day. The daily maximum dose that can be taken is Up to 75mg per.
• For Thrombocytopenia Induced by Chronic Hepatitis C A maximum dose of 75mg per day should be started at 25mg once a day.
• For severe aplastic anemia 75mg once daily is recommended.
• Using water, swallow the pills as a whole. They must not be crushed or broken into half.
• To keep Revolade levels in the bloodstream constant, take one dose at the same time every day.
• Take the drug empty-handed, one hour before or two hours after meals, for optimal effects.
• Take the dosage as soon as you recall if you miss one and it hasn't been more than 12 hours. Never take two doses to make up for one that you missed.

Revolade Drug Interactions:

Some of the known drug interactions with Revolade include:

• Eltrombopag's efficacy can be diminished by drugs that cause liver enzymes to be produced, such as phenytoin, carbamazepine, rifampin, and St. John's Wort.
• Ketoconazole, itraconazole, clarithromycin, and ritonavir are examples of drugs that suppress liver enzymes and can raise eltrombopag levels, which increases the risk of adverse effects.
• Antacids with magnesium, aluminum, or calcium content might reduce eltrombopag absorption. Eltrombopag can be taken at least two hours before or after using antacids.
• Additionally, iron may hinder the absorption of eltrombopag. Eltrombopag should be taken at least two hours before or after iron supplements.
• Since there may be a higher risk of bleeding while using anticoagulants like warfarin with Revolade, close monitoring is necessary.
• Revolade should be taken with caution while taking medications that influence platelet function, such as Clopidogrel or Aspirin.
• NSAIDs, that increase bleeding risk, such as Naproxen and Ibuprofen, should be used with caution.
• Corticosteroids may interact with Revolade and affect platelet counts.
• Revolade may interact with cancer treatments, such as Cytarabine or Etoposide.

Revolade Precautions:

Some of the commonly known precautions to consider while using Revolade are:

• To screen any negative effects, routine monitoring of platelet counts, liver function tests, and other pertinent blood indicators is necessary.
• Increased liver enzymes should be treated right away by changing the dosage or, if required, stopping the drug entirely.
• Alcohol use should be restricted or avoided since it may interact with Revolade and worsen liver problems. Keep an eye out for signs of blood clots, such as abrupt discomfort, swelling, leg redness, chest pain, or shortness of breath.
• Reduce the likelihood of thromboembolic events by minimizing risk factors such as extended periods of immobility. Exercise regularly and drink plenty of water.
• Inform your physician about all of your medication usage, including over-the-counter remedies, vitamins, and pharmaceutical drugs. Antacids, iron supplements, and any other medications that could interfere with Revolade fall under this category.
• If you're having nausea or diarrhea, consider modifying your diet to something blander or smaller, more frequent meals to assist control these symptoms.
• Drink plenty of water to avoid becoming dehydrated, especially if you're having gastrointestinal side effects.
• Keep an eye out for symptoms of an allergic response, such as swelling, itching, rash, or trouble breathing. Any such symptoms should be reported right once to your healthcare physician.
• Choose a healthy lifestyle that consists of a balanced diet, frequent exercise, and enough sleep.

Buy Revolade Online:

Revolade cost varies based on its strength, dosage, quantity, and manufacturer’s product of the country. However Revolade price also fluctuates based on its demand and supply chain as it is highly effective and preferred by healthcare physicians. Revolade price is quite high but one can easily buy Revolade from LifeRx Pharmacy, an online pharmacy platform offering a wide range of generic and brand medications at an affordable price ensuring safety and easy accessibility to customers.

Is Eltrombopag a chemotherapy drug?

No, Eltrombopag is not a chemotherapy medication. It is a thrombopoietin receptor agonist used to raise platelet counts in severe aplastic anemia and persistent immunological thrombocytopenia.

What foods should you avoid when taking Revolade?

Meals high in calcium, such as dairy products, and meals or supplements high in iron should be avoided right before taking Revolade since they may interfere with the medication's absorption.

How long can you take Revolade for?

Revolade dosage is influenced by the specific ailment being treated as well as the reaction of each patient. As directed by your healthcare professional, who will periodically evaluate its efficacy and necessity for continuous usage, it may be used for lengthy periods.

Does Eltrombopag make you tired?

Yes, one of the adverse reactions of Eltrombopag is fatigue or exhaustion. Inform your healthcare practitioner about any substantial exhaustion you have so they can make the necessary modifications or find an alternative.

Can Revolade cause back pain?

Indeed, while it is less frequent, back discomfort is a negative effect of using Revolade. For assessment and treatment, speak with your healthcare professional if you have severe or chronic back pain.

References:

• https://www.drugs.com/uk/revolade.html
• https://www.revolade.com/