Trelegy Ellipta (Fluticasone/Umeclidinium/Vilanterol)

Trelegy Ellipta (Fluticasone/Umeclidinium/Vilanterol) Medication Information:

What is Trelegy Ellipta?

Trelegy Ellipta is an inhalation powder that contains fluticasone, umeclidinium, and vilanterol in doses of 100, 62.5, and 25 micrograms, respectively. Fluticasone is a steroid that suppresses the release of inflammatory chemicals in the body. Umeclidinium is a cholinergic antagonist. A bronchodilator, Vilanterol, is used to open up the airways. These drugs help to breathe by relaxing the muscles in the airways.

Uses of Trelegy Ellipta:

What is it used for?

It is used to treat adults with COPD (chronic obstructive pulmonary disease), such as bronchitis and emphysema, and to prevent bronchospasm. Trelegy Ellipta is also used in adults to prevent and treat asthmatic symptoms, such as wheezing, and to improve breathing.

How does Trelegy Ellipta work?

In individuals with asthma or COPD, Trelegy helps by reducing lung inflammation and relaxing the airways.

Directions For Use:

• Use one inhalation of Trelegy Ellipta one time each day.
• Use Trelegy Ellipta at the same time each day.

For COPD:

The recommended Trelegy dosage for chronic obstructive pulmonary disease (COPD) is one inhalation (puff) of Trelegy Ellipta 100/62.5/25 mcg once a day.

For Asthma:

One inhalation (puff) of Trelegy Ellipta once a day is the recommended dosage for asthma. Your doctor may prescribe Trelegy Ellipta 100/62.5/25 mcg or Trelegy Ellipta 200/62.5/25 mcg for this ailment. Their advice will be based on the severity of your asthma and if you've tried other asthma treatments before. 

Trelegy Ellipta should be taken exactly as directed by your doctor. Read all drug guides or instruction sheets and follow all guidelines on your prescription label. Your doctor may adjust your dose from time to time. Improper usage of this medicine can result in death or major heart adverse effects. It should be used at the same time every day and no more than once per 24 hours.

Doses Available As:

Each Trelegy Ellipta inhaler has 30 doses in total. Inside each inhaler are two foil strips containing blisters of the drug. One strip in each blister contains either 100 mcg* or 200 mcg** of fluticasone; the other strip in each blister contains 62.5 mcg of umeclidinium and 25 mcg of vilanterol.

Maximum Dose:

1 inhalation every 24 hours:

• If you take too much Trelegy Ellipta and experience any odd symptoms, such as worsened shortness of breath, chest pain, elevated heart rate, or shakiness, contact your healthcare provider or go to the nearest hospital emergency room straight away.
• Do not take any other anticholinergic medications for any reason. Check with your doctor or pharmacist to see if any of your other medications are anticholinergic/ long-acting beta2-adrenergic agonist (LABA) medicines.

What to do in an overdose of Trelegy Ellipta?

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canadian residents can call a provincial poison control center. Symptoms of overdose may include: shaking (tremor), chest pain, fast/irregular heartbeat, and seizures.

Always have a rescue inhaler with you to treat sudden symptoms. If you do not have a rescue inhaler, call your healthcare provider to have one prescribed for you. You may report side effects to the FDA at 1-800-FDA-1088.

What if you miss a dose of Trelegy Ellipta?

Use the medicine as soon as possible, but if your next dose is approaching, skip the missed dose. Do not combine two doses at once. On any given day, do not utilize more than one inhalation.

Trelegy Ellipta Precautions:

Here are some general precautions associated with Trelegy Ellipta:

• If you experience symptoms like rash, itching, swelling, or difficulty breathing, seek medical attention immediately.
• People with COPD have a higher risk of pneumonia, and using inhaled corticosteroids, one of the components of Trelegy Ellipta may further increase this risk.
• Long-term use of inhaled corticosteroids, such as the one in Trelegy Ellipta, may affect bone density, potentially leading to osteoporosis.
• Like other corticosteroids, Trelegy Ellipta may increase the risk of developing glaucoma or cataracts. Regular eye exams are recommended while using this medication.
• Corticosteroids can suppress the immune system, making you more susceptible to infections. Avoid contact with people who have contagious illnesses, and promptly report any signs of infection to your healthcare provider.
• Prolonged use of corticosteroids may suppress the adrenal glands' ability to produce hormones, leading to adrenal insufficiency.

Trelegy Ellipta Side Effects:

• Thrush (Fungal infection).
• A Throat Infection Due To Candida Fungus.
• Throat Irritation.
• A Common Cold.
• Inflammation Of The Tissue Lining The Sinuses.
• Myalgia
• Headache
• Cough
• Joint Pain.
• Bone Fracture.
• Worsening of a diabetes control.
• Cardio-vascular effects.
• Glaucoma and Cataract.

Trelegy Ellipta Drug Interactions:

Here are some common drug interactions to be aware of:

• Corticosteroids like Cortisone, Prednisolone etc.
• Beta-blockers, commonly used to treat cardiovascular conditions like Nadalol, and Atenolol.
• Anticholinergic Medications like Atropine, Diphenhydramine.
• Monoamine oxidase inhibitors (MAOIs) like Marplan, Nardil.
• Antifungal Agents: Some antifungal agents, such as Ketoconazole, Itraconazole, and Voriconazole.
• HIV Protease Inhibitors: HIV protease inhibitors, like Ritonavir and Atazanavir.
• Strong CYP3A4 Inhibitors: Drugs that strongly inhibit the cytochrome P450 3A4 enzyme system, such as Clarithromycin, Telithromycin, and Nefazodone
• Diuretics like Furosemide.

Storage:

Store at room temperature away from direct sunlight, heat, and moisture. Do not stock in the bathroom. Throw away the inhaler 6 weeks after first removing it from the tray or when the dose counter reads zero, whichever comes first. Keep all the drugs away from children and pets in any case.

Buy Trelegy Ellipta Online:

Due to the High Trelegy Ellipta price, it tends to cause a hole in the pocket of the consumers. For these expensive medications, like Trelegy, One can buy Trelegy Ellipta online from LifeRx Pharmacy, and it will help Trelegy Ellipta price to go down.

Once you have a prescription, you can buy Trelegy Ellipta from LifeRx Pharmacy. They offer good pricing and many varieties of medication to buy from. Trelegy Ellipta costs are usually high and it poses a problem for customers to avail.

Is Trelegy Ellipta a corticosteroid?

Yes, Trelegy Ellipta contains an inhaled corticosteroid called fluticasone furoate as one of its active ingredients. Corticosteroids help reduce inflammation in the airways, which is beneficial in managing conditions like chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

What tier drug is Trelegy Ellipta?

The tier classification of medications can vary depending on the specific insurance plan and formulary. Generally, Trelegy Ellipta is considered a higher-tier medication due to its cost and the complexity of its formulation. It belongs to Tier 3.

When will Trelegy Ellipta go generic?

Based on a review of the patents and regulatory protections, November 29, 2030, seems to be the earliest date for generic entrance. Buying Trelegy Ellipta online from LifeRx Pharmacy can help people save a lot. Check out the best offers for Trelegy Ellipta cost on LifeRx Pharmacy.

Can you drink alcohol while taking Trelegy Ellipta?

It's generally recommended to avoid excessive alcohol consumption while taking Trelegy Ellipta or any medication, especially if you have a medical condition such as COPD. While moderate alcohol consumption is unlikely to directly interact with Trelegy Ellipta, excessive alcohol intake can have negative effects on your respiratory system and overall health, which may exacerbate COPD symptoms.

Can you use Advair and Trelegy Ellipta together?

Using Advair and Trelegy Ellipta together is generally not recommended because they both contain corticosteroids and long-acting beta2-agonists (LABAs). Using two medications that contain similar active ingredients simultaneously can increase the risk of side effects without providing additional benefits.

References:

• https://www.drugs.com/trelegy-ellipta.html
• https://www.webmd.com/drugs/2/drug-174197/trelegy-ellipta-inhalation/details
• https://www.trelegy.com/
• https://asthma.net/trelegy-ellipta