Valdoxan (Agomelatine)

FREQUENTLY ASKED QUESTIONS (FAQs):

What is Valdoxan?

Valdoxan(Amelatine) is primarily prescribed to adults to manage major depressive disorder (MDD). It's categorized under the drug class, including serotonin (5-HT2C) receptor antagonists and melatonergic agonists. Agomelatine mimics the effects of melatonin, a hormone that controls the cycle of sleep and wakefulness. This promotes healthier sleep patterns and maintains circadian rhythms.

Additionally, it functions as an antagonist at serotonin (5-HT2C) receptors, which are implicated in mood control. Serotonin and norepinephrine levels in specific brain regions are raised due to blocking these receptors, which helps reduce depressive symptoms. Let us learn more about Valdoxan cost and where to buy Valdoxan online.

Uses and Benefits of Valdoxan:

• Adults with major depressive episodes can benefit greatly from the FDA-approved medication Valdoxan.

• Agomelatine functions as a melatonergic agonist and an antagonist of the serotonin (5-HT2C) receptor. It lessens depressive symptoms like sadness, loss of interest, and feelings of worthlessness by raising serotonin and norepinephrine levels in specific brain regions.

• It controls body clocks. As a melatonergic agonist, it mimics the actions of the hormone melatonin, which is involved in controlling sleep. This can help restore circadian rhythms, which are frequently disturbed in depressed people, and enhance the quality of their sleep.

• Valdoxan may also have anti-anxiety qualities. It might reduce the anxiety symptoms that frequently accompany depression.

• It has been reported that Valdoxan has little effect on sexual function. Patients who have experienced sexual side effects from other antidepressants may find this to be especially helpful.

• Valdoxan functions as a melatonergic agonist and a serotonin antagonist, compared with common antidepressants.

• Valdoxan has the potential to improve a patient's overall quality of life greatly. Emotional well-being and better daily functioning are correlated with better sleep and mood.

Side Effects of Valdoxan:

Some common side effects of Valdoxan are:

• Headache

• Feeling lightheaded

• Nausea

• Exhaustion

• Sleep disturbances or insomnia

Some less Common Side Effects include:

• Valdoxan may occasionally impair liver function.

• Some people may become more agitated or anxious, especially at the beginning of their treatment.

• Some patients have reported experiencing weight gain as a side effect of Valdoxan.

• Some people might still have changes in their sexual function or desire.

How to use Valdoxan?

• Effective Valdoxan (Agomelatine) use requires careful doctor adherence to your doctor's directions.

• Always adhere to the dosage recommendations made by your medical professional. Wait to change the dosage or quit taking Valdoxan after first talking to them.

• Valdoxan is typically prescribed at a dose of 25 mg once daily, taken orally.

• Because of its effects on sleep-wake cycles, it is usually taken in the evening, preferably right before bed. Maintaining a regular dosage in your body is facilitated by taking your medication at the same time every day.

• It is recommended to take Valdoxan tablets whole, with water. Chewing or crushing them is not recommended.

• It can be taken with or without food, but to maximize absorption, it is usually advised to take it without.

Drug Interactions:

A few broad details regarding medications and Valdoxan interactions:

• SNRIs and SSRIs like Venlafaxine, Duloxetine, Fluoxetine, and sertraline can raise Serotonin levels.

• Using Valdoxan concurrently with Fluvoxamine can raise blood levels of agomelatine raising the risk of adverse effects.

• Rifampicin can lower blood levels of Valdoxan, hence decreasing the drug's efficacy.

• Fluconazole can raise blood levels of Valdoxan, which may raise the possibility of adverse effects.

Buy Valdoxan Online:

Valdoxan is a brand-prescribed antidepressant medication used to prevent depressive disorder in adults. The Valdoxan cost varies on its strength, dosage, and the local medication dispensing pharmacy. However, on average Valdoxan price for a supply of 84 tablets in a strength of 25 mg is between $250-$350.

One can buy Valdoxan online through LifeRx Pharmacy which provides a wide range of brand-name and generic medications at competitive prices. We promise authorized and secure delivery of medications directly to your home, ensuring convenience and reliability in the process.

Does Valdoxan cause weight gain?

Valdoxan does not frequently cause weight gain to be reported as a side effect. Clinical research indicates that Valdoxan is generally weight-neutral, meaning that most people who take it experience no discernible change in body weight. However, each person may react differently to medication.

What type of antidepressant is Valdoxan?

Being a selective serotonin antagonist and melatonergic agonist, Valdoxan (Agomelatine) is a special kind of antidepressant. Melatonin as a hormone regulates the sleep-wake cycle. MT1 and MT2 melatonin receptors are activated (agonistic) by Valdoxan. Activating these receptors helps Valdoxan regulate circadian rhythms and enhance sleep patterns. At serotonin 5-HT2C receptors, Valdoxan also functions as an antagonist (blocker). The neurotransmitters dopamine and norepinephrine, which are involved in mood regulation, are elevated in particular brain regions as a result of this action.

Is Valdoxan an SSRI?

Valdoxan contains an active ingredient agomelatine which is not an SSRI. Its distinct mechanism of action places it in a different class of antidepressants. Valdoxan is categorized as a melatonergic agonist as well as a selective serotonin antagonist. Due to its unique mode of action, Valdoxan might be worth a try for people who have not reacted well to SSRIs or who have particular symptoms, like insomnia linked to depression.

Can Valdoxan cause anxiety?

When compared to some other antidepressants, Valdoxan typically has a lower incidence of causing anxiety. Like any medication, though, each person will react differently, and some may have anxiety-inducing side effects. A tiny proportion of Valdoxan users reported experiencing anxiety as a side effect. Comparing Valdoxan to SSRIs (Selective Serotonin Reuptake Inhibitors), which are more frequently linked to anxiety as a side effect, the incidence of anxiety is generally lower with Valdoxan.

How does Valdoxan work?

Valdoxan functions via a dual mechanism of action. It mainly affects the brain's serotonin and melatonin receptors. The hormone that is essential for controlling the sleep-wake cycle is melatonin. Valdoxan influences these melatonin receptors, which aids in controlling the cycle of sleep and wakefulness. It is prescribed for those who suffer from depression and might have trouble sleeping, such as insomnia or disturbed sleep. Furthermore, Valdoxan acts as an antagonist at serotonin receptors 5-HT2C. Valdoxan causes an indirect increase in dopamine and norepinephrine levels in specific brain regions by blocking these particular serotonin receptors. This combined effect lessens depressive symptoms and improves mood.

References:

• https://www.pharmacychecker.com/valdoxan/#prices
• https://www.drugs.com/medical-answers/agomelatine-3570346/